Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms

We attempt to address a key question in the joint analysis of transcriptomic data: can we correlate the patterns we observe in transcriptomic datasets to known interactions and pathway knowledge to broaden our understanding of disease pathophysiology? We present a systematic approach that sheds ligh...

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Detalles Bibliográficos
Autores principales: Figueiredo, Rebeca Queiroz, Raschka, Tamara, Kodamullil, Alpha Tom, Hofmann-Apitius, Martin, Mubeen, Sarah, Domingo-Fernández, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373148/
https://www.ncbi.nlm.nih.gov/pubmed/34197603
http://dx.doi.org/10.1093/nar/gkab556

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373148/
https://www.ncbi.nlm.nih.gov/pubmed/34197603
http://dx.doi.org/10.1093/nar/gkab556

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