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A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins

Neuroblastoma is the most common extracranial nervous system tumor in children. It presents with a spectrum of clinical prognostic measures ranging from benign growths that regress spontaneously to highly malignant, treatment evasive tumors affiliated with increased mortality rates. MYCN amplificati...

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Detalles Bibliográficos
Autores principales: El-Soussi, Sarra, Hanna, Reine, Semaan, Hanna, Khater, Amanda-Rose, Abdallah, Jad, Abou-Kheir, Wassim, Abou-Antoun, Tamara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373200/
https://www.ncbi.nlm.nih.gov/pubmed/34422720
http://dx.doi.org/10.3389/fped.2021.693145