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A Novel Therapeutic Mechanism of Imipridones ONC201/ONC206 in MYCN-Amplified Neuroblastoma Cells via Differential Expression of Tumorigenic Proteins
Neuroblastoma is the most common extracranial nervous system tumor in children. It presents with a spectrum of clinical prognostic measures ranging from benign growths that regress spontaneously to highly malignant, treatment evasive tumors affiliated with increased mortality rates. MYCN amplificati...
Autores principales: | El-Soussi, Sarra, Hanna, Reine, Semaan, Hanna, Khater, Amanda-Rose, Abdallah, Jad, Abou-Kheir, Wassim, Abou-Antoun, Tamara |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373200/ https://www.ncbi.nlm.nih.gov/pubmed/34422720 http://dx.doi.org/10.3389/fped.2021.693145 |
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