Dual mTORC1/mTORC2 Inhibition as a Host-Directed Therapeutic Target in Pathologically Distinct Mouse Models of Tuberculosis

Efforts to develop more effective and shorter-course therapies for tuberculosis have included a focus on host-directed therapy (HDT). The goal of HDT is to modulate the host response to infection, thereby improving immune defenses to reduce the duration of antibacterial therapy and/or the amount of...

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Detalles Bibliográficos
Autores principales: Tasneen, Rokeya, Mortensen, Deborah S., Converse, Paul J., Urbanowski, Michael E., Upton, Anna, Fotouhi, Nader, Nuermberger, Eric, Hawryluk, Natalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Experimental Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373221/
https://www.ncbi.nlm.nih.gov/pubmed/33903099
http://dx.doi.org/10.1128/AAC.00253-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373221/
https://www.ncbi.nlm.nih.gov/pubmed/33903099
http://dx.doi.org/10.1128/AAC.00253-21

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