Developing Cyclic Peptomers as Broad-Spectrum Type III Secretion System Inhibitors in Gram-Negative Bacteria

Antibiotic-resistant bacteria are an emerging global health threat. New antimicrobials are urgently needed. The injectisome type III secretion system (T3SS), required by dozens of Gram-negative bacteria for virulence but largely absent from nonpathogenic bacteria, is an attractive antimicrobial targ...

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Detalles Bibliográficos
Autores principales: Lam, Hanh N., Lau, Tannia, Lentz, Adam, Sherry, Jessica, Cabrera-Cortez, Alejandro, Hug, Karen, Lalljie, Annalyse, Engel, Joanne, Lokey, R. Scott, Auerbuch, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Mechanisms of Action: Physiological Effects
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373237/
https://www.ncbi.nlm.nih.gov/pubmed/33875435
http://dx.doi.org/10.1128/AAC.01690-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373237/
https://www.ncbi.nlm.nih.gov/pubmed/33875435
http://dx.doi.org/10.1128/AAC.01690-20

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