Knockdown of astrocytic Grin2a aggravates β‐amyloid‐induced memory and cognitive deficits through regulating nerve growth factor

Synapse degeneration correlates strongly with cognitive impairments in Alzheimer's disease (AD) patients. Soluble Amyloid‐beta (Aβ) oligomers are thought as the major trigger of synaptic malfunctions. Our earlier studies have demonstrated that Aβ oligomers interfere with synaptic function throu...

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Detalles Bibliográficos
Autores principales: Du, Zunshu, Song, Yizhi, Chen, Xinyue, Zhang, Wanning, Zhang, Guitao, Li, Hui, Chang, Lirong, Wu, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373273/
https://www.ncbi.nlm.nih.gov/pubmed/34291567
http://dx.doi.org/10.1111/acel.13437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373273/
https://www.ncbi.nlm.nih.gov/pubmed/34291567
http://dx.doi.org/10.1111/acel.13437

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