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Decreased antiviral immune response within the central nervous system of aged mice is associated with increased lethality of West Nile virus encephalitis

West Nile virus (WNV) is an emerging pathogen that causes disease syndromes ranging from a mild flu‐like illness to encephalitis. While the incidence of WNV infection is fairly uniform across age groups, the risk of lethal encephalitis increases with advanced age. Prior studies have demonstrated age...

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Detalles Bibliográficos
Autores principales: Funk, Kristen E., Arutyunov, Artem D., Desai, Pritesh, White, James P., Soung, Allison L., Rosen, Sarah F., Diamond, Michael S., Klein, Robyn S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373274/
https://www.ncbi.nlm.nih.gov/pubmed/34327802
http://dx.doi.org/10.1111/acel.13412