Inhibition of the neuromuscular acetylcholine receptor with atracurium activates FOXO/DAF‐16‐induced longevity

Transcriptome‐based drug screening is emerging as a powerful tool to identify geroprotective compounds to intervene in age‐related disease. We hypothesized that, by mimicking the transcriptional signature of the highly conserved longevity intervention of FOXO3 (daf‐16 in worms) overexpression, we co...

Descripción completa

Detalles Bibliográficos
Autores principales: McIntyre, Rebecca L., Denis, Simone W., Kamble, Rashmi, Molenaars, Marte, Petr, Michael, Schomakers, Bauke V., Rahman, Mizanur, Gupta, Siddhartha, Toth, Marton L., Vanapalli, Siva A., Jongejan, Aldo, Scheibye‐Knudsen, Morten, Houtkooper, Riekelt H., Janssens, Georges E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373276/
https://www.ncbi.nlm.nih.gov/pubmed/34227219
http://dx.doi.org/10.1111/acel.13381

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373276/
https://www.ncbi.nlm.nih.gov/pubmed/34227219
http://dx.doi.org/10.1111/acel.13381

Ejemplares similares