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Disruption of Glutamate Release and Uptake-Related Protein Expression After Noise-Induced Synaptopathy in the Cochlea

High-intensity noise can cause permanent hearing loss; however, short-duration medium-intensity noise only induces a temporary threshold shift (TTS) and damages synapses formed by inner hair cells (IHCs) and spiral ganglion nerves. Synaptopathy is generally thought to be caused by glutamate excitoto...

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Detalles Bibliográficos
Autores principales: Ma, Kefeng, Zhang, Anran, She, Xiaojun, Yang, Honglian, Wang, Kun, Zhu, Yingwen, Gao, Xiujie, Cui, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373299/
https://www.ncbi.nlm.nih.gov/pubmed/34422838
http://dx.doi.org/10.3389/fcell.2021.720902