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Ganoderic Acid A-Mediated Modulation of Microglial Polarization is Involved in Depressive-Like Behaviors and Neuroinflammation in a Rat Model of Post-Stroke Depression

BACKGROUND: Post-stroke depression (PSD) is a common complication after stroke. Ganoderic acid A (GAA), one of the main bioactive Ganoderma triterpenoids, exerts preventive and therapeutic effects in many diseases. However, the function of GAA in PSD has not been well studied. METHODS: PSD model was...

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Detalles Bibliográficos
Autores principales: Zhang, Ling, Zhang, Lei, Sui, Rubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373311/
https://www.ncbi.nlm.nih.gov/pubmed/34421302
http://dx.doi.org/10.2147/NDT.S317207