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Inhibition of NOD1 Attenuates Neonatal Hypoxia-Ischemia Induced Long-Term Cognitive Impairments in Mice Through Modulation of Autophagy-Related Proteins

BACKGROUND: Autophagy is implicated in neonatal hypoxia-ischemia (HI) induced cognitive impairment. The nucleotide-oligomerizing domain-1 (NOD1), a protein involved in inflammatory responses, has been shown to activate autophagy to promote progression of other diseases. We aimed to investigate wheth...

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Detalles Bibliográficos
Autores principales: Liu, Fang, Shao, Mingyu, Xu, Feng, Rong, Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373312/
https://www.ncbi.nlm.nih.gov/pubmed/34421301
http://dx.doi.org/10.2147/NDT.S314884