Cargando…

A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App (NL−F/NL−F) knock‐in mouse model

Insulin resistance and diabetes mellitus are major risk factors for Alzheimer's disease (AD), and studies with transgenic mouse models of AD have provided supportive evidence with some controversies. To overcome potential artifacts derived from transgenes, we used a knock‐in mouse model, App(NL...

Descripción completa

Detalles Bibliográficos
Autores principales: Mazzei, Guianfranco, Ikegami, Ryohei, Abolhassani, Nona, Haruyama, Naoki, Sakumi, Kunihiko, Saito, Takashi, Saido, Takaomi C., Nakabeppu, Yusaku
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373331/
https://www.ncbi.nlm.nih.gov/pubmed/34245097
http://dx.doi.org/10.1111/acel.13429