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A high‐fat diet exacerbates the Alzheimer's disease pathology in the hippocampus of the App (NL−F/NL−F) knock‐in mouse model
Insulin resistance and diabetes mellitus are major risk factors for Alzheimer's disease (AD), and studies with transgenic mouse models of AD have provided supportive evidence with some controversies. To overcome potential artifacts derived from transgenes, we used a knock‐in mouse model, App(NL...
Autores principales: | Mazzei, Guianfranco, Ikegami, Ryohei, Abolhassani, Nona, Haruyama, Naoki, Sakumi, Kunihiko, Saito, Takashi, Saido, Takaomi C., Nakabeppu, Yusaku |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373331/ https://www.ncbi.nlm.nih.gov/pubmed/34245097 http://dx.doi.org/10.1111/acel.13429 |
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