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Neutralization of oxidized phospholipids attenuates age‐associated bone loss in mice

Oxidized phospholipids (OxPLs) are pro‐inflammatory molecules that affect bone remodeling under physiological conditions. Transgenic expression of a single‐chain variable fragment (scFv) of the antigen‐binding domain of E06, an IgM natural antibody that recognizes the phosphocholine (PC) moiety of O...

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Detalles Bibliográficos
Autores principales: Palmieri, Michela, Almeida, Maria, Nookaew, Intawat, Gomez‐Acevedo, Horacio, Joseph, Teenamol E., Que, Xuchu, Tsimikas, Sotirios, Sun, Xiaoli, Manolagas, Stavros C., Witztum, Joseph L., Ambrogini, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373359/
https://www.ncbi.nlm.nih.gov/pubmed/34278710
http://dx.doi.org/10.1111/acel.13442