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FoxO3 deficiency in cortical astrocytes leads to impaired lipid metabolism and aggravated amyloid pathology

The rise of life expectancy of the human population is accompanied by the drastic increases of age‐associated diseases, in particular Alzheimer's disease (AD), and underscores the need to understand how aging influences AD development. The Forkhead box O transcription factor 3 (FoxO3) is known...

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Detalles Bibliográficos
Autores principales: Du, Shuqi, Jin, Feng, Maneix, Laure, Gedam, Manasee, Xu, Yin, Catic, Andre, Wang, Meng C., Zheng, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373366/
https://www.ncbi.nlm.nih.gov/pubmed/34247441
http://dx.doi.org/10.1111/acel.13432