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The cyto-protective effects of LH on ovarian reserve and female fertility during exposure to gonadotoxic alkylating agents in an adult mouse model

STUDY QUESTION: Does LH protect mouse oocytes and female fertility from alkylating chemotherapy? SUMMARY ANSWER: LH treatment before and during chemotherapy prevents detrimental effects on follicles and reproductive lifespan. WHAT IS KNOWN ALREADY: Chemotherapies can damage the ovary, resulting in p...

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Detalles Bibliográficos
Autores principales: Del Castillo, L M, Buigues, A, Rossi, V, Soriano, M J, Martinez, J, De Felici, M, Lamsira, H K, Di Rella, F, Klinger, F G, Pellicer, A, Herraiz, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373474/
https://www.ncbi.nlm.nih.gov/pubmed/34333622
http://dx.doi.org/10.1093/humrep/deab165