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The cyto-protective effects of LH on ovarian reserve and female fertility during exposure to gonadotoxic alkylating agents in an adult mouse model
STUDY QUESTION: Does LH protect mouse oocytes and female fertility from alkylating chemotherapy? SUMMARY ANSWER: LH treatment before and during chemotherapy prevents detrimental effects on follicles and reproductive lifespan. WHAT IS KNOWN ALREADY: Chemotherapies can damage the ovary, resulting in p...
Autores principales: | Del Castillo, L M, Buigues, A, Rossi, V, Soriano, M J, Martinez, J, De Felici, M, Lamsira, H K, Di Rella, F, Klinger, F G, Pellicer, A, Herraiz, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373474/ https://www.ncbi.nlm.nih.gov/pubmed/34333622 http://dx.doi.org/10.1093/humrep/deab165 |
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