Cargando…

Circumventricular Organ Apelin Receptor Knockdown Decreases Blood Pressure and Sympathetic Drive Responses in the Spontaneously Hypertensive Rat

The central site(s) mediating the cardiovascular actions of the apelin-apelin receptor (APJ) system remains a major question. We hypothesized that the sensory circumventricular organs (CVOs), interfacing between the circulation and deeper brain structures, are sites where circulating apelin acts as...

Descripción completa

Detalles Bibliográficos
Autores principales: Griffiths, Philip R., Lolait, Stephen J., Paton, Julian F. R., O’Carroll, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373520/
https://www.ncbi.nlm.nih.gov/pubmed/34421653
http://dx.doi.org/10.3389/fphys.2021.711041