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Circumventricular Organ Apelin Receptor Knockdown Decreases Blood Pressure and Sympathetic Drive Responses in the Spontaneously Hypertensive Rat
The central site(s) mediating the cardiovascular actions of the apelin-apelin receptor (APJ) system remains a major question. We hypothesized that the sensory circumventricular organs (CVOs), interfacing between the circulation and deeper brain structures, are sites where circulating apelin acts as...
Autores principales: | Griffiths, Philip R., Lolait, Stephen J., Paton, Julian F. R., O’Carroll, Anne-Marie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373520/ https://www.ncbi.nlm.nih.gov/pubmed/34421653 http://dx.doi.org/10.3389/fphys.2021.711041 |
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