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Co-crystallization and structure determination: An effective direction for anti-SARS-CoV-2 drug discovery

Safer and more-effective drugs are urgently needed to counter infections with the highly pathogenic SARS-CoV-2, cause of the COVID-19 pandemic. Identification of efficient inhibitors to treat and prevent SARS-CoV-2 infection is a predominant focus. Encouragingly, using X-ray crystal structures of th...

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Detalles Bibliográficos
Autores principales: Wang, Zhonglei, Yang, Liyan, Zhao, Xian-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373586/
https://www.ncbi.nlm.nih.gov/pubmed/34426762
http://dx.doi.org/10.1016/j.csbj.2021.08.029