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Protective efficacy of Ad26.COV2.S against SARS-CoV-2 B.1.351 in macaques

The emergence of SARS-CoV-2 variants that partially evade neutralizing antibodies poses a threat to the efficacy of current COVID-19 vaccines(1,2). The Ad26.COV2.S vaccine expresses a stabilized spike protein from the WA1/2020 strain of SARS-CoV-2, and has recently demonstrated protective efficacy a...

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Detalles Bibliográficos
Autores principales: Yu, Jingyou, Tostanoski, Lisa H., Mercado, Noe B., McMahan, Katherine, Liu, Jinyan, Jacob-Dolan, Catherine, Chandrashekar, Abishek, Atyeo, Caroline, Martinez, David R., Anioke, Tochi, Bondzie, Esther A., Chang, Aiquan, Gardner, Sarah, Giffin, Victoria M., Hope, David L., Nampanya, Felix, Nkolola, Joseph, Patel, Shivani, Sanborn, Owen, Sellers, Daniel, Wan, Huahua, Hayes, Tammy, Bauer, Katherine, Pessaint, Laurent, Valentin, Daniel, Flinchbaugh, Zack, Brown, Renita, Cook, Anthony, Bueno-Wilkerson, Deandre, Teow, Elyse, Andersen, Hanne, Lewis, Mark G., Martinot, Amanda J., Baric, Ralph S., Alter, Galit, Wegmann, Frank, Zahn, Roland, Schuitemaker, Hanneke, Barouch, Dan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373608/
https://www.ncbi.nlm.nih.gov/pubmed/34161961
http://dx.doi.org/10.1038/s41586-021-03732-8