Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breast

There is an unmet clinical need for stratification of breast lesions as indolent or aggressive to tailor treatment. Here, single-cell transcriptomics and multiparametric imaging applied to a mouse model of breast cancer reveals that the aggressive tumor niche is characterized by an expanded basal-li...

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Detalles Bibliográficos
Autores principales: Sinha, Vidya C., Rinkenbaugh, Amanda L., Xu, Mingchu, Zhou, Xinhui, Zhang, Xiaomei, Jeter-Jones, Sabrina, Shao, Jiansu, Qi, Yuan, Zebala, John A., Maeda, Dean Y., McAllister, Florencia, Piwnica-Worms, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373912/
https://www.ncbi.nlm.nih.gov/pubmed/34408137
http://dx.doi.org/10.1038/s41467-021-25240-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373912/
https://www.ncbi.nlm.nih.gov/pubmed/34408137
http://dx.doi.org/10.1038/s41467-021-25240-z

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