Notch1 haploinsufficiency in mice accelerates adipogenesis

Notch signaling has been recognized recently as a key regulator of metabolism. Here, we determined the role of Notch1 in adipogenesis in wild-type (WT) and Notch1 hetero-mutant (N1+/−) mice provided with 12-week normal or high-fat diet. Haploinsufficiency of Notch1 was associated with adipose tissue...

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Detalles Bibliográficos
Autores principales: Yamaguchi, Kazutoshi, Hayashi, Motoharu, Uchida, Yasuhiro, Cheng, Xian Wu, Nakayama, Takayuki, Matsushita, Tadashi, Murohara, Toyoaki, Takeshita, Kyosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373919/
https://www.ncbi.nlm.nih.gov/pubmed/34408185
http://dx.doi.org/10.1038/s41598-021-96017-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373919/
https://www.ncbi.nlm.nih.gov/pubmed/34408185
http://dx.doi.org/10.1038/s41598-021-96017-z

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