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Improving fragment-based ab initio protein structure assembly using low-accuracy contact-map predictions

Sequence-based contact prediction has shown considerable promise in assisting non-homologous structure modeling, but it often requires many homologous sequences and a sufficient number of correct contacts to achieve correct folds. Here, we developed a method, C-QUARK, that integrates multiple deep-l...

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Detalles Bibliográficos
Autores principales: Mortuza, S. M., Zheng, Wei, Zhang, Chengxin, Li, Yang, Pearce, Robin, Zhang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373938/
https://www.ncbi.nlm.nih.gov/pubmed/34408149
http://dx.doi.org/10.1038/s41467-021-25316-w