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Adipose stem cell niche reprograms the colorectal cancer stem cell metastatic machinery

Obesity is a strong risk factor for cancer progression, posing obesity-related cancer as one of the leading causes of death. Nevertheless, the molecular mechanisms that endow cancer cells with metastatic properties in patients affected by obesity remain unexplored. Here, we show that IL-6 and HGF, s...

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Detalles Bibliográficos
Autores principales: Di Franco, Simone, Bianca, Paola, Sardina, Davide Stefano, Turdo, Alice, Gaggianesi, Miriam, Veschi, Veronica, Nicotra, Annalisa, Mangiapane, Laura Rosa, Lo Iacono, Melania, Pillitteri, Irene, van Hooff, Sander, Martorana, Federica, Motta, Gianmarco, Gulotta, Eliana, Lentini, Vincenzo Luca, Martorana, Emanuele, Fiori, Micol Eleonora, Vieni, Salvatore, Bongiorno, Maria Rita, Giannone, Giorgio, Giuffrida, Dario, Memeo, Lorenzo, Colarossi, Lorenzo, Mare, Marzia, Vigneri, Paolo, Todaro, Matilde, De Maria, Ruggero, Medema, Jan Paul, Stassi, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373975/
https://www.ncbi.nlm.nih.gov/pubmed/34408135
http://dx.doi.org/10.1038/s41467-021-25333-9