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Evidence of new intragenic HBB haplotypes model for the prediction of beta-thalassemia in the Malaysian population

This study sought to determine the potential role of HBB haplotypes to predict beta-thalassemia in the Malaysian population. A total of 543 archived samples were selected for this study. Five tagging SNPs in the beta-globin gene (HBB; NG_000007.3) were analyzed for SNP-based and haplotype associatio...

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Detalles Bibliográficos
Autores principales: Aziz, Nur-Aisyah, Taib, Wan-Rohani Wan, Kharolazaman, Nur-Khairunnisa, Ismail, Imilia, Al-Jamal, Hamid Ali Nagi, Jamil, Nadiah Wan-Arfah Wan Abdul, Esa, Ezalia, Ibrahim, Hishamshah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8373976/
https://www.ncbi.nlm.nih.gov/pubmed/34408192
http://dx.doi.org/10.1038/s41598-021-96018-y