Dosimetric impact of Ac-227 in accelerator-produced Ac-225 for alpha-emitter radiopharmaceutical therapy of patients with hematological malignancies: a pharmacokinetic modeling analysis

BACKGROUND: Actinium-225 is an alpha-particle emitter under investigation for use in radiopharmaceutical therapy. To address limited supply, accelerator-produced (225)Ac has been recently made available. Accelerator-produced (225)Ac via (232)Th irradiation (denoted (225/7)Ac) contains a low percenta...

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Detalles Bibliográficos
Autores principales: Sgouros, George, He, Bin, Ray, Nitya, Ludwig, Dale L., Frey, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374020/
https://www.ncbi.nlm.nih.gov/pubmed/34406515
http://dx.doi.org/10.1186/s40658-021-00410-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374020/
https://www.ncbi.nlm.nih.gov/pubmed/34406515
http://dx.doi.org/10.1186/s40658-021-00410-6

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