Brain-Targeted Polysorbate 80-Emulsified Donepezil Drug-Loaded Nanoparticles for Neuroprotection

Most Alzheimer’s disease drugs do not work efficiently because of the blood–brain barrier. Therefore, we designed a new nanopreparation (PS-DZP-CHP): cholesterol-modified pullulan (CHP) nanoparticle with polysorbate 80(PS) surface coverage, as donepezil (DZP) carrier to realize brain tissue delivery...

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Detalles Bibliográficos
Autores principales: Tao, Xiaojun, Mao, Siyu, Zhang, Qiufang, Yu, Hongyuan, Li, Yu, He, Xiangling, Yang, Shanyi, Zhang, Zhirong, Yi, Ziqi, Song, Yujiao, Feng, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Nano Express
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374023/
https://www.ncbi.nlm.nih.gov/pubmed/34406517
http://dx.doi.org/10.1186/s11671-021-03584-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374023/
https://www.ncbi.nlm.nih.gov/pubmed/34406517
http://dx.doi.org/10.1186/s11671-021-03584-1

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