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Susceptibility loci and polygenic architecture highlight population specific and common genetic features in inguinal hernias: genetics in inguinal hernias

BACKGROUND: The underlying pathology of inguinal hernia is still not fully known; thus, further investigations of genetic backgrounds is needed. Here, we aimed to identify genetic factors attributing to inguinal hernias and explore the polygenic architecture of which some components are population-s...

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Detalles Bibliográficos
Autores principales: Hikino, Keiko, Koido, Masaru, Tomizuka, Kohei, Liu, Xiaoxi, Momozawa, Yukihide, Morisaki, Takayuki, Murakami, Yoshinori, The Biobank Japan Project, Mushiroda, Taisei, Terao, Chikashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374389/
https://www.ncbi.nlm.nih.gov/pubmed/34392144
http://dx.doi.org/10.1016/j.ebiom.2021.103532