Cyclooxygenase-2 regulates PTHrP transcription in human articular chondrocytes and is involved in the pathophysiology of osteoarthritis in rats

BACKGROUND: Cyclooxygenase-2 (COX-2) inhibitors are prescribed for the management of osteoarthritis (OA)-associated pain and inflammation. However, the role of COX-2 in normal and osteoarthritic articular chondrocytes has not been well investigated. We hypothesize that COX-2 plays a role in articula...

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Detalles Bibliográficos
Autores principales: Chang, Ling-hua, Chen, Chung-Hwan, Wu, Shun-Cheng, Chang, Je-ken, Ho, Mei-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374645/
https://www.ncbi.nlm.nih.gov/pubmed/34466385
http://dx.doi.org/10.1016/j.jot.2021.06.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374645/
https://www.ncbi.nlm.nih.gov/pubmed/34466385
http://dx.doi.org/10.1016/j.jot.2021.06.003

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