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Method of targeted bisulfite massive parallel sequencing of the human LINE-1 retrotransposon promoter

The methylation index of the LINE-1 promoter is one of the most commonly used markers for assessing the global level of genome methylation in various human cells and tissues. We developed an NGS-based protocol for DNA methylation analysis of the LINE-1 retrotransposon promoter. This approach allows...

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Detalles Bibliográficos
Autores principales: Vasilyev, Stanislav A., Markov, Anton V., Vasilyeva, Oksana Yu., Tolmacheva, Ekaterina N., Zatula, Lada A., Sharysh, Diana V., Zhigalina, Daria I., Demeneva, Victoria V., Lebedev, Igor N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374674/
https://www.ncbi.nlm.nih.gov/pubmed/34434857
http://dx.doi.org/10.1016/j.mex.2021.101445