The germinal center reaction depends on RNA methylation and divergent functions of specific methyl readers

Long-lasting immunity depends on the generation of protective antibodies through the germinal center (GC) reaction. N(6)-methyladenosine (m(6)A) modification of mRNAs by METTL3 activity modulates transcript lifetime primarily through the function of m(6)A readers; however, the physiological role of...

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Detalles Bibliográficos
Autores principales: Grenov, Amalie C., Moss, Lihee, Edelheit, Sarit, Cordiner, Ross, Schmiedel, Dominik, Biram, Adi, Hanna, Jacob H., Jensen, Torben Heick, Schwartz, Schraga, Shulman, Ziv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374864/
https://www.ncbi.nlm.nih.gov/pubmed/34402854
http://dx.doi.org/10.1084/jem.20210360

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8374864/
https://www.ncbi.nlm.nih.gov/pubmed/34402854
http://dx.doi.org/10.1084/jem.20210360

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