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Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma
PURPOSE: The purpose of this study was to determine the effects of the Sigma-1R (σ-1r) on retinal ganglion cell (RGC) survival following optic nerve crush (ONC) and the signaling mechanism involved in the σ-1r protection. METHODS: The overall strategy was to induce injury by ONC and mitigate RGC dea...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Association for Research in Vision and Ophthalmology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375012/ https://www.ncbi.nlm.nih.gov/pubmed/34406331 http://dx.doi.org/10.1167/iovs.62.10.17 |