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Sigma-1R Protects Retinal Ganglion Cells in Optic Nerve Crush Model for Glaucoma

PURPOSE: The purpose of this study was to determine the effects of the Sigma-1R (σ-1r) on retinal ganglion cell (RGC) survival following optic nerve crush (ONC) and the signaling mechanism involved in the σ-1r protection. METHODS: The overall strategy was to induce injury by ONC and mitigate RGC dea...

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Detalles Bibliográficos
Autores principales:	Li, Linya, He, Shaoqing, Liu, Yang, Yorio, Thomas, Ellis, Dorette Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2021
Materias:	Retina
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375012/ https://www.ncbi.nlm.nih.gov/pubmed/34406331 http://dx.doi.org/10.1167/iovs.62.10.17

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