S100A8/A9 is not essential for the development of inflammation and joint pathology in interleukin-1 receptor antagonist knockout mice

BACKGROUND: Excessive osteoclast activity, which is strongly stimulated by pro-inflammatory mediators, results in bone and cartilage degeneration as central features of many arthritides. Levels of the alarmin S100A8/A9 and interleukin (IL)-1β are both increased in arthritis patients and correlate wi...

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Detalles Bibliográficos
Autores principales: Di Ceglie, Irene, van Lent, Peter L. E. M., Geven, Edwin J. W., Koenders, Marije I., Blom, Arjen B., Vogl, Thomas, Roth, Johannes, van den Bosch, Martijn H. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375068/
https://www.ncbi.nlm.nih.gov/pubmed/34412663
http://dx.doi.org/10.1186/s13075-021-02602-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375068/
https://www.ncbi.nlm.nih.gov/pubmed/34412663
http://dx.doi.org/10.1186/s13075-021-02602-y

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