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A novel RIP1/RIP3 dual inhibitor promoted OPC survival and myelination in a rat neonatal white matter injury model with hOPC graft

BACKGROUND: The dual inhibitors of receptor interacting protein kinase-1 and -3 (RIP1 and RIP3) play an important role in cell death processes and inflammatory responses. White matter injury (WMI), a leading cause of neurodevelopmental disabilities in preterm infants, which is characterized by exten...

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Detalles Bibliográficos
Autores principales: Zhang, Chu, Guan, Qian, Shi, Hao, Cao, Lingsheng, Liu, Jing, Gao, Zixuan, Zhu, Wenxi, Yang, Yinxiang, Luan, Zuo, Yao, Ruiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375070/
https://www.ncbi.nlm.nih.gov/pubmed/34407865
http://dx.doi.org/10.1186/s13287-021-02532-1