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Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease

Converging lines of evidence from several models, and post‐mortem human brain tissue studies, support the involvement of the kynurenine pathway (KP) in Huntington's disease (HD) pathogenesis. Quantifying KP metabolites in HD biofluids is desirable, both to study pathobiology and as a potential...

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Detalles Bibliográficos
Autores principales: Rodrigues, Filipe B., Byrne, Lauren M., Lowe, Alexander J., Tortelli, Rosanna, Heins, Mariette, Flik, Gunnar, Johnson, Eileanoir B., De Vita, Enrico, Scahill, Rachael I., Giorgini, Flaviano, Wild, Edward J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375100/
https://www.ncbi.nlm.nih.gov/pubmed/33797782
http://dx.doi.org/10.1111/jnc.15360