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High-dose radiotherapy in newly diagnosed low-grade gliomas with nonmethylated O(6)-methylguanine-DNA methyltransferase

BACKGROUND: Patients with low-grade gliomas (LGGs) harboring O(6)-methylguanine-DNA methyltransferase promoter nonmethylation (MGMT-non-pM) have a particularly short survival and are great resistance to chemotherapy. The objective of this study was to assess the efficacy of high-dose radiotherapy (R...

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Detalles Bibliográficos
Autores principales: Liu, Yanwei, Li, Yanong, Wang, Peng, Chen, Li, Feng, Jin, Qiu, Xiaoguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375106/
https://www.ncbi.nlm.nih.gov/pubmed/34412650
http://dx.doi.org/10.1186/s13014-021-01878-3