Cargando…
Increased gene expression and copy number of mutated bla(KPC) lead to high-level ceftazidime/avibactam resistance in Klebsiella pneumoniae
BACKGROUND: Resistance to ceftazidime-avibactam was reported, and it is important to investigate the mechanisms of ceftazidime/avibactam resistance in K. pneumoniae with mutations in bla(KPC). RESULTS: We report the mutated bla(KPC) is not the only mechanism related to CZA resistance, and investigat...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375111/ https://www.ncbi.nlm.nih.gov/pubmed/34412588 http://dx.doi.org/10.1186/s12866-021-02293-0 |