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Use of proteomics to identify mechanisms of hepatocellular carcinoma with the CYP2D6*10 polymorphism and identification of ANGPTL6 as a new diagnostic and prognostic biomarker

BACKGROUND: Although an association between the cytochrome P4502D6 (CYP2D6) *10 (100C>T) polymorphism and hepatocellular carcinoma (HCC) is known, the mechanism remains unclear. Here we aimed to explore mechanisms of CYP2D6*10 (100C>T) polymorphism conferring to HCC, and screen markers for HCC...

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Detalles Bibliográficos
Autores principales: Hu, Guiming, Gao, Fei, Wang, Guanzhe, Fang, Yan, Guo, Yuanyuan, Zhou, Jun, Gu, Yuhan, Zhang, Cunzhen, Gao, Na, Wen, Qiang, Qiao, Hailing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375140/
https://www.ncbi.nlm.nih.gov/pubmed/34412629
http://dx.doi.org/10.1186/s12967-021-03038-3