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Exosomal circEIF3K from cancer-associated fibroblast promotes colorectal cancer (CRC) progression via miR-214/PD-L1 axis

BACKGROUND: Tumor microenvironment (e.g., cancer-associated fibroblast) plays a key role in cancer tumorigenesis and metastasis. However, the detailed mechanism of whether hypoxia promotes CRC progression via tumor microenvironment remains unclear. METHODS: In this study, circEIF3K exosome was exami...

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Detalles Bibliográficos
Autores principales: Yang, Kaihua, Zhang, Jie, Bao, Chuanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375187/
https://www.ncbi.nlm.nih.gov/pubmed/34412616
http://dx.doi.org/10.1186/s12885-021-08669-9