Cargando…

MultiK: an automated tool to determine optimal cluster numbers in single-cell RNA sequencing data

Single-cell RNA sequencing (scRNA-seq) provides new opportunities to characterize cell populations, typically accomplished through some type of clustering analysis. Estimation of the optimal cluster number (K) is a crucial step but often ignored. Our approach improves most current scRNA-seq cluster...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Siyao, Thennavan, Aatish, Garay, Joseph P., Marron, J. S., Perou, Charles M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375188/
https://www.ncbi.nlm.nih.gov/pubmed/34412669
http://dx.doi.org/10.1186/s13059-021-02445-5