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MultiK: an automated tool to determine optimal cluster numbers in single-cell RNA sequencing data
Single-cell RNA sequencing (scRNA-seq) provides new opportunities to characterize cell populations, typically accomplished through some type of clustering analysis. Estimation of the optimal cluster number (K) is a crucial step but often ignored. Our approach improves most current scRNA-seq cluster...
Autores principales: | Liu, Siyao, Thennavan, Aatish, Garay, Joseph P., Marron, J. S., Perou, Charles M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375188/ https://www.ncbi.nlm.nih.gov/pubmed/34412669 http://dx.doi.org/10.1186/s13059-021-02445-5 |
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