BC-N102 suppress breast cancer tumorigenesis by interfering with cell cycle regulatory proteins and hormonal signaling, and induction of time-course arrest of cell cycle at G1/G0 phase

Mechanisms of breast cancer progression and invasion, often involve alteration of hormonal signaling, and upregulation and/or activation of signal transduction pathways that input to cell cycle regulation. Herein, we describe a rationally designed first-in-class novel small molecule inhibitor for ta...

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Detalles Bibliográficos
Autores principales: Lawal, Bashir, Kuo, Yu-Cheng, Wu, Alexander T. H., Huang, Hsu-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375223/
https://www.ncbi.nlm.nih.gov/pubmed/34421361
http://dx.doi.org/10.7150/ijbs.62808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375223/
https://www.ncbi.nlm.nih.gov/pubmed/34421361
http://dx.doi.org/10.7150/ijbs.62808

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