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BC-N102 suppress breast cancer tumorigenesis by interfering with cell cycle regulatory proteins and hormonal signaling, and induction of time-course arrest of cell cycle at G1/G0 phase
Mechanisms of breast cancer progression and invasion, often involve alteration of hormonal signaling, and upregulation and/or activation of signal transduction pathways that input to cell cycle regulation. Herein, we describe a rationally designed first-in-class novel small molecule inhibitor for ta...
Autores principales: | Lawal, Bashir, Kuo, Yu-Cheng, Wu, Alexander T. H., Huang, Hsu-Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375223/ https://www.ncbi.nlm.nih.gov/pubmed/34421361 http://dx.doi.org/10.7150/ijbs.62808 |
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