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Rapamycin and trametinib: a rational combination for treatment of NSCLC

Mammalian target of rapamycin (mTOR) is one of the most commonly activated pathways in human cancers, including lung cancer. Targeting mTOR with molecule inhibitors is considered as a useful therapeutic strategy. However, the results obtained from the clinical trials with the inhibitors so far have...

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Detalles Bibliográficos
Autores principales: Sun, Chao-Yue, Li, Yi-Zhuo, Cao, Di, Zhou, Yu-Feng, Zhang, Mei-Yin, Wang, Hui-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375233/
https://www.ncbi.nlm.nih.gov/pubmed/34421360
http://dx.doi.org/10.7150/ijbs.62752