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UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185

Background: Esophageal cancer is the sixth-most common fatal malignant tumor worldwide. Little is known regarding the genetic drivers that influence targeted therapy outcomes in patients with esophageal cancer. Exploring the pathogenesis of this lethal tumor could provide clues for developing approp...

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Detalles Bibliográficos
Autores principales: Zheng, Zhikun, Zhang, Bin, Yu, Haixin, Li, Shoukang, Song, Naicheng, Jin, Xin, Li, Jinsong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375240/
https://www.ncbi.nlm.nih.gov/pubmed/34421347
http://dx.doi.org/10.7150/ijbs.61117