Targeting Soluble Epoxide Hydrolase and Cyclooxygenases Enhance Joint Pain Control, Stimulate Collagen Synthesis, and Protect Chondrocytes From Cytokine-Induced Apoptosis

Objective: To determine the symptomatic and disease-modifying capabilities of sEH and COX inhibitors during joint inflammation. Methods: Using a blinded, randomized, crossover experimental design, 6 adult healthy horses were injected with lipopolysaccharide (LPS; 3 μg) from E. coli in a radiocarpal...

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Detalles Bibliográficos
Autores principales: Tucker, Laura, Trumble, Troy N., Groschen, Donna, Dobbs, Erica, Baldo, Caroline F., Wendt-Hornickle, Erin, Guedes, Alonso G. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375305/
https://www.ncbi.nlm.nih.gov/pubmed/34422942
http://dx.doi.org/10.3389/fvets.2021.685824

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375305/
https://www.ncbi.nlm.nih.gov/pubmed/34422942
http://dx.doi.org/10.3389/fvets.2021.685824

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