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Establishment of Mouse Primed Stem Cells by Combination of Activin and LIF Signaling

In mice, embryonic stem cells (ESCs) and epiblast stem cells (EpiSCs) are established from pre- and post-implantation embryos and represent the naive and primed state, respectively. Herein we used mouse leukemia inhibitory factor (LIF), which supports ESCs self-renewal and Activin A (Act A), which i...

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Detalles Bibliográficos
Autores principales: Wei, Mengyi, Chen, Yanglin, Zhao, Chaoyue, Zheng, Li, Wu, Baojiang, Chen, Chen, Li, Xihe, Bao, Siqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8375391/
https://www.ncbi.nlm.nih.gov/pubmed/34422831
http://dx.doi.org/10.3389/fcell.2021.713503