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Ileocolonic Healing After Extended Small Bowel Resection in Mice: NOD2 Deficiency Impairs Anastomotic Healing and Postoperative Outcome

BACKGROUND: Nucleotide-binding oligomerization domain-containing protein 2 (NOD2) mutations are a genetic risk factor for Crohn disease. Ileocecal resection is the most often performed surgery in Crohn disease. We investigated the effect of Nod2 knockout (KO) status on anastomotic healing after exte...

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Detalles Bibliográficos
Autores principales: Witte, Maria, Reiner, Johannes, Bannert, Karen, Jaster, Robert, Maschmeier, Christian, Schafmayer, Clemens, Lamprecht, Georg, Berlin, Peggy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8376130/
https://www.ncbi.nlm.nih.gov/pubmed/33555306
http://dx.doi.org/10.1093/ibd/izab022